AKR7A2 Antikörper
Kurzübersicht für AKR7A2 Antikörper (ABIN7111415)
Target
Alle AKR7A2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- AKR7A2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
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Andere Bezeichnung
- AKR7A2
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Hintergrund
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Synonyms: Aflatoxin B1 aldehyde reductase member 2|AFB1 aldehyde reductase 1 (AFB1-AR 1)|Aldoketoreductase 7|Succinic semialdehyde reductase (SSA reductase)|AKR7A2|AFAR|AFAR1|AKR7
Background: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 40 kDa
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Gen-ID
- 8574
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UniProt
- O43488
Target
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